Egyptian Wild Cat - Wild cat from tomb number 3 at Beni Hasan. The tomb of Khnumhotep II, one of the most notable at Beni Hasan, dates to the early 12th Dynasty (1991-1783 BCE...
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Dr. Grann is Clinical Professor of Medicine and Epidemiology and Health Policy & Management, College of Physicians & Surgeons and Mailman School of Public Health, Columbia University. A medical oncologist for more than 30 years, in 1977 he received both his M.P.H. degree in Health Policy and Management (Health Outcomes) at Columbia University and a Clinical Research Training Grant from the American Cancer Society (CRTG-98-260-02).
His work has focused on quality of life, studies of preferences of breast cancer patients, cost-effectiveness, and decision analysis of heath outcomes related to genetic mutations in breast/ovarian cancer. He also is interested in disparities of care especially in clinical trials.
He works in the Women’s Cancer Chemotherapy Clinic at Columbia, where breast cancer patients are evaluated and treated, and is Principal Investigator of the NSABP Study of tamoxifen and raloxifene (STAR) trial for the Cancer Center. Presently he is Director of the Recruitment Core at the Herbert Irving Comprehensive Cancer Center.
|Association may affect disparities in disease treatment and outcomes for cancer therapy|
Researchers from Columbia University Mailman School of Public Health and the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center, have found a strong association between women of African descent from the U.S. and Caribbean, who are otherwise healthy, and the prevalence of neutropenia, or low white blood count. Neutropenia, which is associated with race and ethnicity, has essentially been unexplained and, although thought to be benign, may affect therapy for cancer or other illnesses. Among women of African descent who develop a malignancy, this association may contribute to racial disparities in treatment and outcomes. The study findings are reported online in Blackwell Publishing Ltd. British Journal of Hematology.
"The goal of our study was to learn as much as we could about the association between a single nucleotide polymorphism (SNP), which creates a person's unique DNA sequence, and low white blood cell counts (WBC)," said Victor, R. Grann, MD, professor of Epidemiology and Health Policy and Management at Columbia University Mailman School of Public Health, professor of Medicine at the Columbia University College of Physicians & Surgeons, director of Research Recruitment and Minority Outreach of the Herbert Irving Comprehensive Cancer Center (HICCC) , and study lead author.
The research compared the data of women from the Caribbean and the United States and is the first to confirm the relationship between these study markers and ethnicity in the absence of disease. In addition to prevalence in African and Afro-Caribbean populations, about 25 percent of all blacks in the United States, including those from other origins, are neutropenic.