These news tips provide information reported from research presented at the American Heart Association’s High Blood Pressure research 2010 Scientific Sessions.
New research points to the existence of a gene on chromosome 5 that influences how much aldosterone is produced — which may be excessive in African-descended populations.
“Aldosterone was very important to their early ancestors living in the arid climate of Africa,” said J. Howard Pratt, study co-author. “Dietary intake of sodium in today’s world is much higher, and there may not be the need for the amount of aldosterone produced, leading to a level of sodium balance that places individuals at risk for hypertension.”
After adjusting for the effects of age, gender and body mass index on plasma aldosterone concentration and blood pressure, genes account for 34 percent of the variation in aldosterone concentration among individuals, and about 25 percent of the variation in systolic and diastolic blood pressure, according to Candace M. Kammerer, study co-author.
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